英文文献综述
英文文献综述
英文文献综述示例：
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Introduction
The literature review is a systematic and critical evaluation of the existing research on a particular topic. It provides an overview of the key themes, gaps, and areas for future research. A well-written literature review can help readers quickly and easily understand the current state of knowledge on a topic。（来源：2024-04-29）
Background
MicroRNAs （miRNAs） have emerged as a class of small non-coding RNAs that play a crucial role in the regulation of gene expression. In recent years, miRNAs have gained significant attention in the field of oncology, particularly in the context of cancer diagnosis and prognosis.（来源：2024-04-29）
Objectives
The purpose of this review is to summarize the current understanding of the role of miRNAs in cancer diagnosis, with a focus on their potential as biomarkers, particularly in the detection methods used for blood and tissue samples.（来源：2024-04-29）
Methods
A systematic search was conducted using multiple electronic databases, including PubMed, Google Scholar, and Scopus. The search strategy included keywords related to miRNAs, cancer diagnosis, and biomarkers. Studies that met the following criteria were included: （1） published in peer-reviewed journals, （2） written in English, （3） focused on miRNAs in cancer diagnosis, （4） used human subjects, and （5） included a detailed description of the diagnostic methods used.
Results
The review identified several key themes, including the identification of specific miRNAs associated with cancer, the development of diagnostic tests based on miRNA expression profiles, and the validation of miRNAs as biomarkers for cancer detection. However, it also highlighted several challenges, such as the limited specificity and sensitivity of current diagnostic methods and the need for further research to understand the biological mechanisms underlying miRNA deregulation in cancer.
Discussion
The findings of this review suggest that miRNAs hold promise as biomarkers for cancer diagnosis. However, there is still a need for comprehensive research to optimize diagnostic methods and improve their clinical utility. Future research should also explore the potential of miRNAs as therapeutic targets and in personalized medicine.
Conclusion
In conclusion, this review provides a critical analysis of the current literature on miRNAs in cancer diagnosis. While there has been significant progress in the field, further research is needed to fully understand the role of miRNAs in cancer and to develop more effective diagnostic tools.
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